![Selektivnaya modifikaciya tetragidrohromeno[2,3-d]pirimidin-2-onov](/upload/12631c5e396938a702bdd516ae8c4208/journals/cover/3392b55ff4c4ee74e3d663233621e912.jpeg)
Yaroslavl, Yaroslavl, Russian Federation
Yaroslavl, Yaroslavl, Russian Federation
from 01.01.2023 until now
Yaroslavl State Technical University
from 01.01.2018 to 01.01.2023
Yaroslavl, Yaroslavl, Russian Federation
graduate student
Yaroslavl, Yaroslavl, Russian Federation
student
Yaroslavl, Yaroslavl, Russian Federation
V dannoy rabote predstavleny rezul'taty sinteza i harakteristiki semi novyh proizvodnyh tetragidrohromeno[2,3-d]pirimidin-2-onov, poluchennyh putem selektivnoy modifikacii gidroksil'noy gruppy v polozhenii S-8. Reakcii alkilirovaniya i acetilirovaniya byli uspeshno ispol'zovany dlya vvedeniya zamestiteley v molekulu, chto pozvolilo poluchit' seriyu novyh geterociklicheskih soedineniy s vyhodami do 94 %. Harakteristika poluchennyh soedineniy provedena metodami YaMR-spektroskopii (¹H i ¹³C), a takzhe mass-spektrometrii.
tetragidrohromeno[2,3-d]pirimidin-2-ony, iodistyy metil, angidrid uksusnoy kisloty, alkilirovanie, acilirovanie
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