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SINTEZ, FLUORESTSENTNYE I ANTIBAKTERIAL'NYE SVOISTVA N-(2’-AMINOARIL)ZAMESHCHENNYKH 1,2,4-OKSADIAZOL-5(4N)-ONOV Sintez, fluorestsentnye i antibakterial'nye svoistva N-(2’-aminoaril)zameshchennykh 1,2,4-oksadiazol-5(4N)-onov

Published in From Chemistry Towards Technology Step-By-Step · Volume 7, Issue 2 · Pages 8–15 · Rubric: Scientific articles
DOI: https://doi.org/10.52957/2782-1900-2026-7-2-8-15
Received: 29.04.2026 Accepted: 08.06.2026 Published: 18.06.2026
Sintezirovan ryad iz vos'mi novyh 2’-aminoariloksadiazol-5(4N)-onov po reakcii vosstanovleniya sootvetstvuyuschih nitroproizvodnyh hloridom olova (II). Izucheny antibakterial'nye i fluorescentnye svoystva proizvodnyh. Naydeno soedinenie s umerennoy antibakterial'noy aktivnost'yu v otnoshenii chuvstvitel'nogo shtamma grampolozhitel'noy bakterii Staphylococcus aureus ATCC-25923 (3-amino-4-(3-(3,4-dihlorfenil)-5-okso-1,2,4-oksadiazol-4(5H)-il)-benzonitril, MIK 64 mkg/ml). Soedineniya prodemonstrirovali slabye fluorescentnye svoystva pri obluchenii svetom λ = 355 nm.
Oksadiazol-5(4N)-on, Vosstanovlenie, Hlorid olova(II), Antibakterial'naya aktivnost', fluorescenciya
Funding
This work was supported by Saint Petersburg State University (project № 126022017742-6)
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