DIASTEREOSELECTIVE SYNTHESIS OF CHROMENO[4,3-D]PYRIMIDINES
Abstract and keywords
Abstract (English):
The paper investigates the diastereoselective synthesis of chromeno[4,3-d]pyrimidines by isolation and cyclization of diastereomerically pure dihydropyrimidine addition intermediates to resorcinol. The authors discovered the reversibility of the addition reaction to be an important factor that could neutralize the dominant formation of one of the intermediate diastereomers.

Keywords:
hexahydrochromeno[4,3-d]pyrimidines, resorcinol, acid-catalyzed condensation, diastereoselectivity
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References

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