From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 82518 10.52957/27821900_2021_04_43 Научные статьи Scientific articles Научные статьи Nitrogen-containing heterocyclic O-, and S-nucleophiles in reactions with 4-nitrophthalonitrile and 4-bromo-5-nitrophthalonitrile Использование азотсодержащих гетероциклических O-, и S-нуклеофилов в реакциях с 4-нитрофталонитрилом и 4-бром-5-нитрофталонитрилом Абрамов Игорь Геннадьевич Abramov Igor Gennadevich abramovig@ystu.ru

доктор химических наук;

doctor of chemical sciences;

 Баклагин Вячеслав Леонидович Baklagin Vyacheslav Leonidovich Макарова Елена Сергеевна Makarova Elena Sergeevna makarovaes@ystu.ru

кандидат химических наук;

candidate of chemical sciences;

 Клейкова Дарья Эдуардовна Kleikova Dar'ya Eduardovna Ярославский государственный технический университет Yaroslavl State Technical University 23 12 2021 23 12 2021 2 4 43 49 21 11 2021 09 12 2021 https://chemintech.ru/en/nauka/article/82518/view

На основе SNAr-реакции между 4-нитрофталонитрилом, 4-бром-5-нитрофталонитрилом и фенолами (тиолами), содержащими различные по своей природе гетероциклические системы, разработан метод синтеза не описанных в литературе моно- и дизамещённых орто-дикарбонитрилов, содержащих 5- и 6-членные гетероциклические фрагменты.

Authors developed a new method for the synthesis of mono- and disubstituted ortho-dicarbonitriles containing 5- and 6-membered heterocyclic moieties based on the SNAr-reaction between 4 nitrophthalonitrile, 4-bromo-5-nitrophthalonitrile and phenols (thiols) containing various heterocyclic systems.

 4-нитрофталонитрил 4-бром-5-нитрофталонитрил активированное ароматическое нуклеофильное замещение замещённые орто-дикарбонитрилы гетероциклические фенолы гетероциклические тиолы 4-nitrophthalonitrile 4-bromo-5-nitrophthalonitrile activated aromatic nucleophilic substitution substituted ortho-dicarbonitriles heterocyclic phenols heterocyclic thiols

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