From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 80868 10.52957/2782-1900-2024-5-1-33-39 Научные статьи Scientific articles Научные статьи Main and by-processes at 1-(2-nitroaryl)-1H-benzotriazole reduction Основной и побочный процессы при восстановлении 1-(2-нитроарил)-1Н-бензотриазола Бегунов Роман Сергеевич Begunov Roman Sergeevich begunov@bio.ac.ru

кандидат химических наук;

candidate of chemical sciences;

 Савина Луиза Ильинична Savina Luisa Ilyinichna luizasavina2000@mail.ru Хлопотинин Александр Игоревич Khlopotinin Alexander Igorevich Ярославский государственный медицинский университет Yaroslavl State Medical University Ярославский государственный университет им. П.Г. Демидова P.G. Demidov Yaroslavl State University 23 03 2024 23 03 2024 5 1 33 39 14 02 2024 12 03 2024 https://chemintech.ru/en/nauka/article/80868/view

Изучено влияние концентрации HCl на протекание основного и побочных процессов при восстановлении 1-(2-нитроарил)-1Н-бензотриазола хлоридом олова (II) в кислой водно-спиртовой среде. При низком содержании HCl в реакционной массе отмечалось образование помимо целевого аминопроизводного еще и азоксисоединения. Использование 36%-ной соляной кислоты приводило к протеканию процесса алкилирования образующегося аминосоединения спиртом, который применялся в качестве растворителя.

The paper investigates the HCl concentration impact on the main and by-processes during the reduction of 1-(2-nitroaryl)-1H-benzotriazole by tin (II) chloride in acidic aqueous-alcoholic medium. The authors have observed the formation of azoxy compounds in addition to the target amino derivative at low HCl content in the reaction mass. The use of 36% hydrochloric acid causes the alkylation of the formed amino compound with alcohol as a solvent.

 восстановление конденсация алкилирование 1-(2-аминоарил)-1Н-бензотриазолы азоксибензол алкиламины reduction condensation alkylation 1-(2-aminoaryl)-1H-benzotriazoles azoxybenzene alkylamines

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