From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 6abe399bf4b84442e8578152 10.52957/2782-1900-2026-7-3-168-179 Научные статьи Scientific articles Научные статьи Cysteinate coordination compounds of copper (II), models of their formation processes Cysteinate coordination compounds of copper (II), models of their formation processes Бобоназарзода Гулрухсор Бобоназар Bobonazarzoda Gulrukhsor Bobonazar еshova81@mail.ru

кандидат химических наук;

candidate of chemical sciences;

 https://orcid.org/0000-0002-0277-3758 Давлатшоева Джахонгул Асановна Davlatshoeva Dzhahongul Asanovna

кандидат химических наук;

candidate of chemical sciences;

 https://orcid.org/0000-0002-1349-2476 Рахимова Мубаширхон Rakhimova Mubashirhon

доктор химических наук;

doctor of chemical sciences;

 Мираминзода Фарида Miraminzoda Farida miraminzoda@mail.ru Научно-исследовательский институт Таджикского национального университета Душанбе Таджикистан Research Institute of the Tajik National University Dushanbe Tajikistan Таджикский национальный университет Душанбе Tajik National University Dushanbe Научно-исследовательский институт Таджикского национального университета Душанбе Таджикистан Research Institute of the Tajik National University Dushanbe Tajikistan 02 10 2026 02 10 2026 7 3 168 179 28 05 2026 14 09 2026 © 2026 Бобоназарзода Г.Б., Давлатшоева Д.А., Рахимова М., Мираминзода Ф. © 2026 Bobonazarzoda G.B., Davlatshoeva D.A., Rakhimova M., Miraminzoda F. 2026 Бобоназарзода Гулрухсор Бобоназар, Давлатшоева Джахонгул Асановна, Рахимова Мубаширхон, Мираминзода Фарида Bobonazarzoda Gulrukhsor Bobonazar, Davlatshoeva Dzhahongul Asanovna, Rakhimova Mubashirhon, Miraminzoda Farida Эта статья доступна по лицензии Creative Commons Attribution 4.0 International (CC BY 4.0) This article is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0) https://chemintech.ru/en/nauka/publications/6abe399bf4b84442e8578152/view

The complexation of copper in aqueous solutions of L-cysteine was studied by the oxidative potential method using a copper amalgam electrode in the pH range of 1.0–8.0 at a temperature of 298 K and an ionic strength of the solution (NaNO3) of I = 1.00 mol/L. The composition was identified and the stepwise formation constants of the complexes were calculated. The following mononuclear copper(II) compounds [CuCys(H2O)3]2+; [Cu(Cys)(OH)(H2O)2]+; [Cu(OH)2(H2O)2]0; [Cu(Cys)(L)(H2O)2]+ are formed in the system. According to the experimental data obtained, the composition, stability, regions of existence, and degrees of accumulation of cysteinate coordination compounds of copper were determined in agreement with the oxidative function and the proposed principle of equilibrium modeling. The calculated model parameters can be used as reference material for the targeted synthesis of complexes and for thermodynamic calculations.

The complexation of copper in aqueous solutions of L-cysteine was studied by the oxidative potential method using a copper amalgam electrode in the pH range of 1.0–8.0 at a temperature of 298 K and an ionic strength of the solution (NaNO3) of I = 1.00 mol/L. The composition was identified and the stepwise formation constants of the complexes were calculated. The following mononuclear copper(II) compounds [CuCys(H2O)3]2+; [Cu(Cys)(OH)(H2O)2]+; [Cu(OH)2(H2O)2]0; [Cu(Cys)(L)(H2O)2]+ are formed in the system. According to the experimental data obtained, the composition, stability, regions of existence, and degrees of accumulation of cysteinate coordination compounds of copper were determined in agreement with the oxidative function and the proposed principle of equilibrium modeling. The calculated model parameters can be used as reference material for the targeted synthesis of complexes and for thermodynamic calculations.

 EMF complex copper(II) cysteine iteration formation constants mole fractions regions of existence distribution diagrams. EMF complex copper(II) cysteine iteration formation constants mole fractions regions of existence distribution diagrams. The study was performed within the framework of a project of the Research Institute of Tajik National University.

Wang W.H., Rusin O., Xu X., Kim K.K., Escobedo J.O., Fakayode S.O., Fletcher K.A., Lowry M., Schowalter C.M., Lawrence C.M., Fronczek F.R., Warner I.M., Strongin R.M. Detection of homocysteine and cysteine. J. Am. Chem. Soc., 2005, 127(45), 15949–15958. DOI: 10.1021/ja054962n. Wang W.H., Rusin O., Xu X., Kim K.K., Escobedo J.O., Fakayode S.O., Fletcher K.A., Lowry M., Schowalter C.M., Lawrence C.M., Fronczek F.R., Warner I.M., Strongin R.M. Detection of homocysteine and cysteine. J. Am. Chem. Soc., 2005, 127(45), 15949–15958. DOI: 10.1021/ja054962n. Dugas H., Penney C. Bioorganic Chemistry: A Chemical Approach to Enzyme Action. New York: Springer, 1981, 512 p. Dugas H., Penney C. Bioorganic Chemistry: A Chemical Approach to Enzyme Action. New York: Springer, 1981, 512 p. Alekseev V.G., Semenov A.N., Pakhomov P.M. Complexation of Ag+ ions with L‑cysteine. Russ. J. Inorg. Chem., 2012, 57, 1041–1044. DOI: 10.1134/S0036023612070029. Alekseev V.G., Semenov A.N., Pakhomov P.M. Complexation of Ag+ ions with L‑cysteine. Russ. J. Inorg. Chem., 2012, 57, 1041–1044. DOI: 10.1134/S0036023612070029. Mironov I.V., Kharlamova V.Y. Gold(I) cysteinate complexes in aqueous solutions. Russ. J. Inorg. Chem., 2017, 62, 1014–1020. DOI: 10.1134/S0036023617070154. Mironov I.V., Kharlamova V.Y. Gold(I) cysteinate complexes in aqueous solutions. Russ. J. Inorg. Chem., 2017, 62, 1014–1020. DOI: 10.1134/S0036023617070154. Bobonazarzoda G.B. Study of complexation processes in the Cu(Hg)–Cu(II)–L‑Val–H2O system using the potentiometry method. Theor. Found. Chem. Eng., 2025, 59, 778–784. DOI: 10.1134/S0040579525602420. Bobonazarzoda G.B. Study of complexation processes in the Cu(Hg)–Cu(II)–L‑Val–H2O system using the potentiometry method. Theor. Found. Chem. Eng., 2025, 59, 778–784. DOI: 10.1134/S0040579525602420. Eshova G.B., Davlatshoeva J.A., Miraminzoda F., Rakhimova M. Study of the Process of Complex Formation between Cu2+ Ion and L-Aminopropionic Acid in Aqueous Solution. Russ. J. Phys. Chem., 2024, 98, 577–582. DOI: 10.1134/S0036024424040071. Eshova G.B., Davlatshoeva J.A., Miraminzoda F., Rakhimova M. Study of the Process of Complex Formation between Cu2+ Ion and L-Aminopropionic Acid in Aqueous Solution. Russ. J. Phys. Chem., 2024, 98, 577–582. DOI: 10.1134/S0036024424040071. Kvyatkovskaya L.V., Mansurov M.M., Yakubov Kh.M. Redox‑metric study of copper (II) complexation in aqueous solutions of monobasic acids. Dushanbe: TSU, 1987, 32 p. (in Russian). Kvyatkovskaya L.V., Mansurov M.M., Yakubov Kh.M. Redox‑metric study of copper (II) complexation in aqueous solutions of monobasic acids. Dushanbe: TSU, 1987, 32 p. (in Russian). Zavorotny V.L., Kalacheva N.A. Methodological guide to laboratory work in analytical chemistry. Titrimetric analysis. Moscow: Gubkin Russian State University of Oil and Gas, 2007. 34 p. (in Russian). Zavorotny V.L., Kalacheva N.A. Methodological guide to laboratory work in analytical chemistry. Titrimetric analysis. Moscow: Gubkin Russian State University of Oil and Gas, 2007. 34 p. (in Russian). Chirkst D.E., Cheremisina O.V., Ivanov I.I., Chistyakov A.A., Lobacheva O.L., Litvinova T.E. Quantitative analysis. Methodological guidelines for laboratory work. St. Petersburg: St. Petersburg State Mining Institute, 2010, 54 p. (in Russian). Chirkst D.E., Cheremisina O.V., Ivanov I.I., Chistyakov A.A., Lobacheva O.L., Litvinova T.E. Quantitative analysis. Methodological guidelines for laboratory work. St. Petersburg: St. Petersburg State Mining Institute, 2010, 54 p. (in Russian). Tensina E.K., Khrapskaya T.A., Kitaeva V.G. Determination of copper(II) in the medicinal preparation "Copper sulfate" by iodometric titration and complexometry. Abstracts of the XXII Russian Youth Scientific Conference. Yekaterinburg: Ural University Publishing House, 2012, 158–159. (in Russian). Tensina E.K., Khrapskaya T.A., Kitaeva V.G. Determination of copper(II) in the medicinal preparation "Copper sulfate" by iodometric titration and complexometry. Abstracts of the XXII Russian Youth Scientific Conference. Yekaterinburg: Ural University Publishing House, 2012, 158–159. (in Russian). Pravilova S.D., Chaplinsky E.F., Ivanova T.A. Determination of alkali concentration in a laboratory chemistry practicum. Modern High Technologies, 2013, 9, 62–63. (in Russian). Pravilova S.D., Chaplinsky E.F., Ivanova T.A. Determination of alkali concentration in a laboratory chemistry practicum. Modern High Technologies, 2013, 9, 62–63. (in Russian). Vasiliev V.P. Thermodynamic properties of electrolyte solutions. Moscow: Vysshaya Shkola, 1982, 320 p. (in Russian). Vasiliev V.P. Thermodynamic properties of electrolyte solutions. Moscow: Vysshaya Shkola, 1982, 320 p. (in Russian). Levanov A.V., Isaikina O.Y., Lunin, V.V. Determining the Potential of a Silver/Silver Chloride Electrode at Different Temperatures. Russ. J. Phys. Chem., 2019, 93, 770–773. DOI: 10.1134/S0036024419040186. Levanov A.V., Isaikina O.Y., Lunin, V.V. Determining the Potential of a Silver/Silver Chloride Electrode at Different Temperatures. Russ. J. Phys. Chem., 2019, 93, 770–773. DOI: 10.1134/S0036024419040186. Yusupov Z.N. Method for determining the composition and formation constants of coordination compounds. Patent RT No. TJ 295. Application No. 37000501, 2001. (in Russian). Yusupov Z.N. Method for determining the composition and formation constants of coordination compounds. Patent RT No. TJ 295. Application No. 37000501, 2001. (in Russian). Dolzhenkov V.A., Kolesnikov Yu.V. Microsoft Excel 2002. The most complete guide. St. Petersburg: BHV Petersburg, 2002, 1053 p. (in Russian). Dolzhenkov V.A., Kolesnikov Yu.V. Microsoft Excel 2002. The most complete guide. St. Petersburg: BHV Petersburg, 2002, 1053 p. (in Russian). Cummings S. VBA for Dummies, 3rd ed. Foster City, CA: IDG Books Worldwide, 1999. 432 p. Cummings S. VBA for Dummies, 3rd ed. Foster City, CA: IDG Books Worldwide, 1999. 432 p. Walkenbach J. Excel 2013 Formulas. Hoboken, NJ: John Wiley & Sons, 2013. 864 p. Walkenbach J. Excel 2013 Formulas. Hoboken, NJ: John Wiley & Sons, 2013. 864 p. Isaac M.P., Finkov M.V. Graphs, formulas, data analysis in Excel. Step-by-step examples. St. Petersburg: Nauka i Tekhnika, 2023, 384 p. (in Russian). Isaac M.P., Finkov M.V. Graphs, formulas, data analysis in Excel. Step-by-step examples. St. Petersburg: Nauka i Tekhnika, 2023, 384 p. (in Russian).