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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">From Chemistry Towards Technology Step-By-Step</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">From Chemistry Towards Technology Step-By-Step</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>От химии к технологии шаг за шагом</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="online">2782-1900</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">83182</article-id>
   <article-id pub-id-type="doi">10.52957/27821900_2020_01_168</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Научные статьи</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>Scientific articles</subject>
    </subj-group>
    <subj-group>
     <subject>Научные статьи</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">Development of a method for the synthesis of CpG-oligonucleotides promising for immunotherapy of cancer</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Development of a method for the synthesis of CpG-oligonucleotides promising for immunotherapy of cancer</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Идилов</surname>
       <given-names>Магомед-Амин Исаевич</given-names>
      </name>
      <name xml:lang="en">
       <surname>Idilov</surname>
       <given-names>Magomed-Amin Isaevich</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Биотехнологическая компания «MDinc»</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Biotechnological company «MDinc»</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2020-12-31T00:00:00+03:00">
    <day>31</day>
    <month>12</month>
    <year>2020</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2020-12-31T00:00:00+03:00">
    <day>31</day>
    <month>12</month>
    <year>2020</year>
   </pub-date>
   <volume>1</volume>
   <issue>1</issue>
   <fpage>168</fpage>
   <lpage>172</lpage>
   <history>
    <date date-type="received" iso-8601-date="2020-09-16T00:00:00+03:00">
     <day>16</day>
     <month>09</month>
     <year>2020</year>
    </date>
    <date date-type="accepted" iso-8601-date="2020-10-20T00:00:00+03:00">
     <day>20</day>
     <month>10</month>
     <year>2020</year>
    </date>
   </history>
   <self-uri xlink:href="https://chemintech.ru/en/nauka/article/83182/view">https://chemintech.ru/en/nauka/article/83182/view</self-uri>
   <abstract xml:lang="ru">
    <p>This article describes a new method for the synthesis of 2`-O-methoxymethyl monomers applicable for the efficient automated synthesis of 2`-O-modified oligoribonucleotides used for immunotherapy of oncological diseases localized in the gastrointestinal tract.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>This article describes a new method for the synthesis of 2`-O-methoxymethyl monomers applicable for the efficient automated synthesis of 2`-O-modified oligoribonucleotides used for immunotherapy of oncological diseases localized in the gastrointestinal tract.</p>
   </trans-abstract>
   <kwd-group xml:lang="en">
    <kwd>CpG oligonucleotides</kwd>
    <kwd>oligoribonucleotides</kwd>
    <kwd>immunotherapy</kwd>
    <kwd>oncology</kwd>
   </kwd-group>
  </article-meta>
 </front>
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