From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 82272 10.52957/27821900_2022_03_106 Научные статьи Scientific articles Научные статьи Synthesis of pyridine- and piperidine-containing polycyclic compounds based on 2,6-dinitrohalogenbenzenes Synthesis of pyridine- and piperidine-containing polycyclic compounds based on 2,6-dinitrohalogenbenzenes Мохова Любовь Андреевна Mokhova Lyubov Andreevna Соколов Александр Андреевич Sokolov Aleksandr Andreevich Ярославский государственный университет им. П.Г. Демидова P.G. Demidov Yaroslavl State University Ярославский государственный технический университет Yaroslavl State Technical University 23 09 2022 23 09 2022 3 3 106 115 01 09 2022 19 09 2022 https://chemintech.ru/en/nauka/article/82272/view

This article deals with the study of the nitration of 4-chloro-3-nitrobenzoic acid. The substrate is highly deactivated for SEAr reactions and therefore strict conditions are required (anhydrous KNO3 in concentrated H2SO4 at 165 °C for 10 hours). We have developed methods for the transformation of 4-chloro-3,5-dinitrobenzoic acid and its ester into new polycyclic systems containing pyridine or piperidine fragments by quaternization and reduction reactions.

This article deals with the study of the nitration of 4-chloro-3-nitrobenzoic acid. The substrate is highly deactivated for SEAr reactions and therefore strict conditions are required (anhydrous KNO3 in concentrated H2SO4 at 165 °C for 10 hours). We have developed methods for the transformation of 4-chloro-3,5-dinitrobenzoic acid and its ester into new polycyclic systems containing pyridine or piperidine fragments by quaternization and reduction reactions.

 4-chloro-3-nitrobenzoic acid N-(2 6-dinitroaryl)pyridinium salts N-(2 6-dinitroaryl)piperidines nitration pyridine quaternisation This work was carried out with the financial support of grant No MK-3459.2022.1.3 from the President of the Russian Federation for state support of young Russian scientists - can-didates of science.

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