From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 82265 10.52957/27821900_2022_03_48 Научные статьи Scientific articles Научные статьи Synthesis of pyridine- and piperidine-containing polycyclic compounds based on 2,6-dinitrohalogenbenzenes Синтез пиридин- и пиперидинсодержащих полициклических соединений на основе 2,6-динитрогалогенбензолов Мохова Любовь Андреевна Mokhova Lyubov Andreevna Соколов Александр Андреевич Sokolov Aleksandr Andreevich Ярославский государственный университет им. П.Г. Демидова P.G. Demidov Yaroslavl State University Ярославский государственный технический университет Yaroslavl State Technical University 23 09 2022 23 09 2022 3 3 48 57 01 09 2022 19 09 2022 https://chemintech.ru/en/nauka/article/82265/view

Исследовано нитрование 4-хлор-3-нитробензойной кислоты. Субстрат является сильно дезактивированным для реакций SEAr, и требуются жесткие условия для их проведения (безводный KNO3 в концентрированной H2SO4 при 165 °С в течение 10 часов). Разработаны методики превращения 4-хлор-3,5-динитробензойной кислоты и её сложного эфира в новые полициклические системы, содержащие пиридиновый или пиперидиновый фрагменты в реакциях кватернизации и восстановления.

This article deals with the study of the nitration of 4-chloro-3-nitrobenzoic acid. The substrate is highly deactivated for SEAr reactions and therefore strict conditions are required (anhydrous KNO3 in concentrated H2SO4 at 165 °C for 10 hours). We have developed methods for the transformation of 4-chloro-3,5-dinitrobenzoic acid and its ester into new polycyclic systems containing pyridine or piperidine fragments by quaternization and reduction reactions.

 4-хлор-3-нитробензойная кислота соли N-(2 6-динитроарил)-пиридиния N-(2 6-динитроарил)-пиперидины нитрование кватернизация пиридина 4-chloro-3-nitrobenzoic acid N-(2 6-dinitroaryl)pyridinium salts N-(2 6-dinitroaryl)piperidines nitration pyridine quaternisation Работа выполнена при финансовой поддержке гранта Президента Российской Федерации для государственной поддержки молодых российских ученых – кандидатов наук № МК-3459.2022.1.3. This work was carried out with the financial support of grant No MK-3459.2022.1.3 from the President of the Russian Federation for state support of young Russian scientists - can-didates of science.

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