From Chemistry Towards Technology Step-By-Step From Chemistry Towards Technology Step-By-Step От химии к технологии шаг за шагом 2782-1900 81126 10.52957/2782-1900-2024-4-4-82-88 Научные статьи Scientific articles Научные статьи Synthesis of N-substituted heterocycles in a sealed Monowave 50 reactor Синтез N-замещенных гетероциклов в герметичном реакторе Monowave 50 Савина Луиза Ильинична Savina Luisa Ilyinichna luizasavina2000@mail.ru Соколов Александр Андреевич Sokolov Aleksandr Andreevich Ярославский государственный медицинский университет Yaroslavl State Medical University Ярославский государственный университет им. П.Г. Демидова P.G. Demidov Yaroslavl State University Ярославский государственный технический университет Yaroslavl State Technical University 23 12 2023 23 12 2023 4 4 82 88 28 10 2023 15 11 2023 https://chemintech.ru/en/nauka/article/81126/view

Осуществлён процесс ароматического нуклеофильного замещения в 2-хлорнитробензоле и 2,4-дихлор-1,5-динитробензоле в реакторе для синтеза Monowave 50. Установлено ускорение реакций субстратов с азагетероциклическими соединениями (пиридином или индолом) в герметично закрытых сосудах.

The paper examines the process of aromatic nucleophilic substitution in 2-chloronitrobenzene and 2,4-dichloro-1,5-dinitrobenzene in a Monowave 50 synthesis reactor. The authors identify accelerated reactions of substrates with azaheterocyclic compounds (pyridine or indole) in hermetically sealed vessels.

 2-хлорнитробензол 2 4-дихлор-1 5-динитробензол азагетероциклы реактор Monowave 50 ароматическое нуклеофильное замещение 2-chloronitrobenzene 2 4-dichloro-1 5-dinitrobenzene azaheterocycles Monowave 50 reactor aromatic nucleophilic substitution

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